Category Archives: Technology

16Oct/17
Image Courtesy of Forbes

When it Comes to 3D Printing, the Future is Already Here

Webinar Availalbe On-Demand – Experts Share Real World Insights 

By:  Eric Luyer, Market Research Analyst

According to the FDA, when it comes to 3D printing, you might say that the future is already here. Due to its versatility, the agency is evaluating the applications of 3D printing in devices, drugs and biologics and to medical applications across the entire ecosystem.

To gain first hand insight on the use of 3D printing in Life Sciences and Healthcare, Axendia assembled an expert panel for a roundtable discussion:3d printing panelists

  • Thomas Marchand, Co-Founder & CEO of BIOMODEX provided the industry perspective
  • Jenny Chen, a trained neuro-radiologist and founder/CEO of 3DHEALS, shared the physician’s perspective
  • Stavros Stefanis, leader in Deloitte’s Product Development practice, shared insights on the use of 3D printing across the product development lifecycle

The webinar was held on September 28th and sponsored by Dassault Systèmes (3DS).

3D printing in Life-Sciences is NOT Science Fiction, it is Science FACT

To date, FDA has cleared over 85 applications for 3D-printed medical devices which span across many product lines such as prosthetics and implants and last year, FDA approved the first 3D printed Drug – Aprecia’s Spritam. Continue reading

11Oct/17
SIAC17

New Versions of Everything, New Expectations

Realizing the Digital Twin – 2017 Siemens Analyst Conference

By:  Sandra K. Rodriguez, Market Analyst

The Siemens Analyst Conference took place in Boston from September 6 – 7, 2017.  Dr. Jan Mrosik, CEO Siemens Digital Factory Division, opened the conference with a clear message:

“Digitalization changes everything and a common digital thread enables continuous business transformation!”

Siemens has invested $6.5B since 2013 in its digital enterprise suite, beginning with the acquisition of LMS International which expanded its strategy for system validation and verification.  The company is also seeking to establish a leadership role in electronics and semiconductor product and process simulation by adding Mentor Graphics to its Digital Factory division.

A Digital Twin is not a concept, it is a disruptive technology.  It enables companies to competitively change the way products are realized, come to life and evolve.  Adding digital twin technology within a smart factory offers companies three unique benefits:

  • The ability to predict profitability through analysis of production scenarios
  • Improved efficiencies through the digital thread and virtual commissioning
  • Optimized production through the comparison of real and digital production systems

Continue reading

07Sep/17
cyber security copy

FDA confirms: Hacking a pacemaker only requires commercially available equipment

By: Giselle C. Matlis, Research Assistant

On August 29, 2017 the FDA published a Safety Communication, Firmware Update to Address Cybersecurity Vulnerabilities Identified in Abbott’s (formerly St. Jude Medical’s) Implantable Cardiac Pacemakers , where they announced that they have reviewed information concerning potential cybersecurity vulnerabilities associated with implantable cardiac pacemakers.cyber security copy

In its Safety Communication, FDA confirmed that if exploited, these vulnerabilities could allow an unauthorized user with commercially available equipment to access a patient’s device and could be used to modify programming commands to the implanted pacemaker.  This could result in patient harm from rapid battery depletion or administration of inappropriate pacing. At this point, there have been no known patient harm, however, the FDA has approved a firmware update that addresses these cybersecurity vulnerabilities and reduces the risk of exploitation and subsequent patient harm.

In fact, former Vice President Dick Cheney discussed his fears that terrorists could hack into his pacemaker, a fear he saw come to life while watching an episode of “Homeland.”Indeed, when doctors implanted Cheney’s pacemaker in 2007, they disabled the wireless feature out of fear that someone could manipulate it and disrupt his heartbeat.

The FDA has been warning about cybersecurity on medical devices for over a decade.  As Eric Luyer stated in his March 2017 article “the time to implement a proactive, comprehensive risk management program to eliminate cybersecurity threats is now”.

Cybersecurity of connected medical devices must be a key step in the design process.  Medical Device manufacturers must be proactive instead of reactive to cybersecurity concerns when developing new products.

24Aug/17
3DS-Life-Modeling

Engineering the Precision Medicine Revolution

From Quantum Mechanics to Population Health Modeling

By:  Daniel R. Matlis, President

“The Holy Grail of Life Science and Healthcare is the development of a virtual human model; to enable medical experiments in-silico, rather than in-vivo[i].” That was the opening line of my 2015 Dassault Systèmes Analyst Conference Brief: “Medical Experiments on your Digital Twin

At this year’s conference, Dassault Systèmes demonstrated that they are at the forefront of engineering the Precision Medicine Revolution.  The company’s goal is to unify the real and virtual worlds, to optimize Patient and Physician experience through the best collaborative science.

Healthcare is shifting away from episodic care at a hospital or a medical practitioner’s office. There is also a movement away from the traditional reactive model healthcare to proactively addressing potential issues and offering preventive care.  This is driving Life-Science organizations to engineer more holistic and personalized approaches to care.

Continue reading

26Jul/17
New Idea

#newidea or #throwbackthursday?

By: Giselle C. Matlis, Research Assistant

Outcome based Medicine

On Monday June 26th 2017, Medtronic announced that they will be using a “new outcomes-based [payment] agreement with Aetna (NYSE:AET) for type 1 and type 2 diabetes patients”. Hooman Hakami, president of the Diabetes Group at Medtronic stated that “this agreement reinforces our shift towards value-based healthcare. We know technology alone isn’t enough and ultimately improved outcomes are what matter…Our goal is to continue to lead by driving innovation that demonstrably improves patient outcomes, elevates patient experience and lowers the total cost of care”.

This sounds like a great new idea.

Ironically, Axendia President, Daniel Matlis, predicted this ten years ago!

In a June 4, 2007 blog post on Axendia.com, Mr. Matlis noted that Sear’s Craftsman line of tools had a lifetime guarantee. This was a business decision by Sears to gamble that the high quality of their tools would minimize warranty costs. He then suggested that a similar approach could work in the healthcare industry and projected that out-come based billing would be the next big thing for the pharmaceutical world. He stated that this approach could, “enable a new health care paradigm, where all involved have the proverbial ‘skin in the game’. Patients get access to drugs that are nearly certain to be effective. Health care payers can ‘afford’ to make new, and let’s face it, expensive, treatments available to patients since they are provided a degree of confidence of treatment effectiveness, and limited downside through a refund”.

So, you decide: #newidea or #throwbackthursday?